Watching my German shorthaired pointer dog successfully recover from multiple hind limb surgeries in her old age led me to wonder how the body naturally copes with the healing process. In the mouse brain, my previous research also showed smooth recovery after a nerve crush that was aided by the very fast response and assistance of immune cells called macrophages. Such observations made me curious about the properties and functions of macrophages, and whether they remember what they have done the last time they were helpful. This project will allow me to follow individual macrophages as they carry out their task to rescue our organs after an injury.
The Klaus Tschira Boost Fund enables me to collaborate with outstanding junior scientists from world-class institutions while we establish our careers. Together with Dr. Franziska Denk (Wolfson Centre for Age-related Diseases, King's College London) and Dr. Tristan Qingyun Li (Stanford University School of Medicine), I will investigate the activity and lifespan of macrophages in different types of brain injuries using sophisticated techniques for single-cell analyses. It is my great pleasure and honour to lead this study, through which we also aim to enhance international scientific cooperation. Furthermore, we share the common aspiration of promoting diversity and equality for women and minorities in science.
... would follow up on our year-long podcast with a hilarious vlog starring Scarlet my three-legged dog!
Name: Dr. Tuan Leng Tay
Research field: Neurobiology
Institution: Albert Ludwig University of Freiburg / Institute of Biology I / Department of Developmental Biology